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Luma Insider
Wellness Health 5 min read

Top 5 NAD+ Supplements in 2025

Author Jake L.

Jake L.

US Army Veteran • Tuesday 24 , 2025

NAD (Nicotinamide Adenine Dinucleotide) is one of the most promising natural compounds for supporting healthy cellular energy, DNA repair, and the aging process.

Backed by dozens of clinical studies, it’s quickly becoming a go-to supplement for those seeking natural longevity and mitochondrial support. But not all NAD supplements are created equal. Some are under-dosed, use ineffective precursor forms (like NMN or NR), or are filled with unnecessary ingredients. That’s why we reviewed the leading options and ranked the Top 5 NAD Supplements of 2025.

What to Look For in a NAD+ Supplement

  • High Dose of Pure NAD+

    You want a supplement that delivers at least 500 mg of NAD+. Make sure the dosage refers to actual NAD+ and not a blend of different filler ingredients. High-quality products clearly list their dosage and form.

  • Made in the USA & Third-Party Tested

    Always choose a supplement that’s made in the USA under strict quality standards. To ensure purity and safety, look for products that are independently tested by third-party labs.

  • Money-Back Guarantee

    Brands that offer a 90-day guarantee show confidence in their product. It gives you time to try the supplement and feel the difference—risk-free.

  • Fair and Hassle-Free Returns

    It should be easy to return a product if it doesn’t work for you. Avoid brands with unclear or restrictive return policies—look for those that make the process simple and honest.

What to Avoid

  • Underdosed blends

    Some brands hide low amounts of NAD+ inside proprietary blends. Always look for clearly labeled doses of pure NAD+.

  • No 3rd-party testing

    Without third-party testing, you can’t be sure what’s really in the bottle. Choose supplements that are tested for purity and potency.

  • No refund policy

    If there’s no money-back guarantee, think twice. Reliable brands make it easy to return a product if it doesn’t work for you.

  • The Cheapest Option

    Cheaper products often mean weak doses, fillers, or poor sourcing. For something you take daily, it’s worth paying for quality.

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Top 5 NAD+ Supplements in 2025

1. Luma Nutrition's NAD+

by Luma Nutrition

Product image
A+ Overall Grade *
Product image
Overall Grade * A+
REVIEW SCORE 4.9 EXCELLENT
BASED ON 1,477 REVIEWS
  • Benefit icon 1
    American Made

    Made in the USA in an FDA-regulated facility. Luma Nutrition adheres to Good Manufacturing Practices (GMPs).

  • Benefit icon 2
    Premium Quality

    Luma Nutrition uses the highest quality NAD+

  • Benefit icon 3
    3rd Party Tested for Potency & Safety

    An independent lab tests all Luma Nutrition products to make sure they’re potent and free from harmful substances.

  • Benefit icon 4
    90 Day Return Policy

    Luma Nutrition offers a fair, 90-day, risk-free, money-back guarantee. If you don't like the product, simply return it for a refund.

  • Made in
    the USA
  • Contains 4,000 FU Of NAD+
  • 90 Day Money Back Guarantee
  • 3rd Party Tested For Safety

Pros

  • Contains quality ingredients
  • Positive verified reviews
  • Subscribe & Save options

Cons

  • Sometimes runs out of stock
  • Only available online
Overall

Our Luma Nutrition NAD+ earns our top spot with a clean, high-potency formula and excellent quality control. With 500 mg of pure NAD+, it delivers a very powerful dosage—no blends or fluff. Luma's 90-day refund policy adds peace of mind, making this a smart, safe choice for anyone serious about their health.

$44.99 $23.99 /Per Bottle
  • Sell Out Risk: High
  • FREE shipping
  • 90-Day Guarantee
*Scores and results are based on our ranking system and do no necessarily reflect typical results from the use of these products. Please visit product websites for more information.

2. NutraBio NMN Supplement

by NutraBio

Product image
B+ Overall Grade *

Pros

  • Contains quality NAD+
  • Positive reviews
  • Solid brand

Cons

  • Expensive

OVERALL

Number two on our list is NutraBio NMN Supplement by NutraBio.

This is a well regarded brand, but the biggest problem is that it only contains NMN which is only a precursor to NAD+.

The price is also quite high. Definitely a more expensive option.

Overall, NutraBio NMN Supplement does use good ingredients, but fall short as it is only using the precursor.

*Scores and results are based on the our ranking system and do not necessarily reflect typical results from the use of these products.

Please visit product websites for more information.

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3. ProHealth Pure NMNH

by ProHealth

Product image
B Overall Grade *

Pros

  • Reputable brand
  • Good dosage

Cons

  • Uses a precursor
  • Most expensive option

OVERALL

Number three on our list is ProHealth Pure NMNH.

This is a well regarded brand, but the biggest problem is that it only contains NMNH which is only a precursor to NAD+.

The price is also quite high. This one was by far the most expensive option that we evaluated.

*Scores and results are based on the our ranking system and do not necessarily reflect typical results from the use of these products.

Please visit product websites for more information.

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4. Advanced NAD+ Supplement

by Cata-Kor

Product image
B- Overall Grade *

Pros

  • Good quality and dosage of NAD

Cons

  • Expensive
  • Contains low dosages of other ingredient

OVERALL

Number four on our list is Advanced NAD+ Supplement by Cata-Kor.

This is a decent option, but the biggest problem is that it contains a low dosage of a different ingredient.

The price is also quite high.

*Scores and results are based on the our ranking system and do not necessarily reflect typical results from the use of these products.

Please visit product websites for more information.

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5. NAD Supplement 8457mg

by thinbi

Product image
C- Overall Grade *

Pros

  • None

Cons

  • Low dosages of way too many ingredients

OVERALL

Number five on our list is NAD Supplement 8457mg bythinbi.

There are just way too many ingredients in this product and none of them are at an effective dosage.

*Scores and results are based on the our ranking system and do not necessarily reflect typical results from the use of these products.

Please visit product websites for more information.

View Product Details (opens in new tab)

Top Rated NAD+ Supplement

#1 Choice Product Image
Luma Nutrition’s NAD+ for Cellular Energy & Healthy Aging
  • 500 mg of the best NAD+
  • Boosts Cellular Energy (Mitochondrial Function): NAD+ is critical for the processes that generate energy (ATP) inside the mitochondria of every cell.
  • Supports DNA Repair: As you age, DNA damage accumulates; NAD+ is required by enzymes (PARPs) that are essential for DNA repair and genomic stability.
  • Promotes Healthy Aging (Sirtuins): NAD+ fuels sirtuins, often called "longevity genes," which are a class of enzymes that regulate cellular health, metabolism, and lifespan.
  • Made in USA & 3rd party tested for purity and quality
  • Sell Out Risk: High
  • FREE shipping
  • 90-Day Guarantee
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What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of your body. It's essential for life—but in recent years, it’s gained attention for one powerful reason: it helps regulate cellular metabolism, DNA repair, and overall longevity—naturally.

Dozens of studies show that NAD+ powers key enzymes called sirtuins, which play a major role in how your body manages cellular stress and the aging process.

That’s why many people take it to support:

  • Healthy aging and longevity
  • Optimal energy production (mitochondrial function)
  • Cellular repair and resilience